Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Good
Based on 3 Reviews
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Organic Turmeric BlendOrganic Turmeric Root Extract standardized to 95% curcuminoids, Organic Fermented Turmeric Root (blend yielding 100 mg curcuminoids)
553 mg
+
Organic Fermented Ginger Root
50 mg
+
Organic Black Pepper Fruit Extract
7 mg
+
Probiotic Blend Bifidobacterium lactis Bl-04Lactobacillus acidophilus La-14
4 mg
+
Top Medical Research Studies
8
We explored the potential of curcumin, the active component of turmeric, in treating vulvovaginal candidiasis, a common yeast infection primarily caused by Candida albicans. Our investigation focused on the substance’s antifungal properties against various strains of Candida, comparing its effectiveness to traditional treatments.
The study involved several methods, including an in vitro assessment where curcumin’s ability to combat yeast was tested against eight different Candida strains. We also examined how curcumin interacts with ergosterol, a vital component of the yeast cell membrane, which could explain its antifungal action. Furthermore, we conducted an in vivo experiment using rats treated with estrogen to simulate conditions that might lead to yeast infections.
Results showed that curcumin had a minimum inhibitory concentration ranging from 125 to 1000μg/ml, with the most significant effect observed against the Candida glabrata strain. Additionally, in the rat model, treatment with curcumin successfully reduced the fungal load in infected subjects after a week. This demonstrates promising potential for curcumin as an effective antifungal agent in treating yeast infections.
The study involved several methods, including an in vitro assessment where curcumin’s ability to combat yeast was tested against eight different Candida strains. We also examined how curcumin interacts with ergosterol, a vital component of the yeast cell membrane, which could explain its antifungal action. Furthermore, we conducted an in vivo experiment using rats treated with estrogen to simulate conditions that might lead to yeast infections.
Results showed that curcumin had a minimum inhibitory concentration ranging from 125 to 1000μg/ml, with the most significant effect observed against the Candida glabrata strain. Additionally, in the rat model, treatment with curcumin successfully reduced the fungal load in infected subjects after a week. This demonstrates promising potential for curcumin as an effective antifungal agent in treating yeast infections.
Read More
8
We examined the impact of turmeric, specifically its active ingredient curcumin, on yeast infections caused by Candida albicans. This was done through a process called antimicrobial photodynamic therapy, or aPDT, which combines light with the photosensitizer curcumin to create oxidative stress that can reduce the yeast's ability to thrive.
Throughout the study, we tested different concentrations of curcumin along with another photosensitizer, Photodithazine, and various LED light intensities. We measured how effective these combinations were by looking at the changes in key genes related to the yeast's adhesion and biofilm formation, as well as its response to oxidative stress.
Our findings showed that aPDT using curcumin resulted in decreased expression of several genes in Candida albicans. Notably, higher concentrations of curcumin led to a more pronounced reduction in gene activity associated with yeast growth and survival.
Overall, our research suggests that combining turmeric with light therapy can significantly impact the functionality of yeast, paving the way for potential new treatments for yeast infections. However, while promising, this treatment approach is still part of a broader therapy and not solely reliant on turmeric alone.
Throughout the study, we tested different concentrations of curcumin along with another photosensitizer, Photodithazine, and various LED light intensities. We measured how effective these combinations were by looking at the changes in key genes related to the yeast's adhesion and biofilm formation, as well as its response to oxidative stress.
Our findings showed that aPDT using curcumin resulted in decreased expression of several genes in Candida albicans. Notably, higher concentrations of curcumin led to a more pronounced reduction in gene activity associated with yeast growth and survival.
Overall, our research suggests that combining turmeric with light therapy can significantly impact the functionality of yeast, paving the way for potential new treatments for yeast infections. However, while promising, this treatment approach is still part of a broader therapy and not solely reliant on turmeric alone.
Read More
7
We conducted an in-depth review to understand whether curcumin, a natural compound found in turmeric, could serve as an effective alternative treatment for oral yeast infections, specifically oral candidiasis. Our research involved sifting through various studies that used a method called antimicrobial photodynamic therapy (aPDT) combined with curcumin to see its effects on Candida species, the fungi responsible for these infections.
From an initial pool of 757 studies, we focused on 26 that met our strict criteria, including laboratory studies and clinical trials. Our findings revealed that in several lab-based tests, curcumin-mediated aPDT completely eliminated yeast cells in some cases. However, for biofilms, which are clusters of yeast that can be more resistant to treatment, we only observed partial growth inhibition and reduction in biofilm mass.
When examining the effectiveness in live animal models, the results were encouraging, with notable antifungal activity observed. Yet, while the preclinical insights are promising, we found that the clinical implications still require further exploration through additional randomized control trials.
In summary, while curcumin shows potential in battling oral candidiasis, we are clear that more research is essential before it can be established as a standard treatment option.
From an initial pool of 757 studies, we focused on 26 that met our strict criteria, including laboratory studies and clinical trials. Our findings revealed that in several lab-based tests, curcumin-mediated aPDT completely eliminated yeast cells in some cases. However, for biofilms, which are clusters of yeast that can be more resistant to treatment, we only observed partial growth inhibition and reduction in biofilm mass.
When examining the effectiveness in live animal models, the results were encouraging, with notable antifungal activity observed. Yet, while the preclinical insights are promising, we found that the clinical implications still require further exploration through additional randomized control trials.
In summary, while curcumin shows potential in battling oral candidiasis, we are clear that more research is essential before it can be established as a standard treatment option.
Read More
Most Useful Reviews
9
Amazing results
2 people found this helpful
I was struggling with yeast infections and warts, but now the results are astonishing. Thank you very much.
Read More
9
Highly recommended
1 people found this helpful
This is excellent for treating yeast infections. I highly recommend it!
Read More
7.5
Effective against infections
1 people found this helpful
I’ve used this product several times, and it effectively combats yeast infections, particularly in the urinary tract. It’s high quality, packed with antioxidants, and the inflammation decreases with use. The taste is also acceptable.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
- All Researches
9.5
We explored the potential of turmeric, specifically curcumin, in treating Candida albicans, a common cause of yeast infections. Our study was designed to assess how effective photodynamic therapy (PDT) could be when combined with curcumin and methylene blue as photosensitizers, alongside different laser exposures.
In our experiments, we looked at 150 samples of a standard strain of Candida albicans. These samples were exposed to various combinations of curcumin and methylene blue under specific laser settings. After a detailed process of culturing and incubation, we were able to count the colony-forming units to determine the effectiveness of the treatments.
The results were rather intriguing; we observed that curcumin combined with a 460-nm laser significantly reduced the number of yeast colonies compared to other treatments. In fact, this combination demonstrated the highest antifungal efficiency, with results markedly better than any control group.
Overall, our findings suggest that turmeric, through its active compound curcumin, shows promise in combatting yeast infections when used in conjunction with photodynamic therapy.
In our experiments, we looked at 150 samples of a standard strain of Candida albicans. These samples were exposed to various combinations of curcumin and methylene blue under specific laser settings. After a detailed process of culturing and incubation, we were able to count the colony-forming units to determine the effectiveness of the treatments.
The results were rather intriguing; we observed that curcumin combined with a 460-nm laser significantly reduced the number of yeast colonies compared to other treatments. In fact, this combination demonstrated the highest antifungal efficiency, with results markedly better than any control group.
Overall, our findings suggest that turmeric, through its active compound curcumin, shows promise in combatting yeast infections when used in conjunction with photodynamic therapy.
Read More
9
We explored the effectiveness of curcumin, a compound in turmeric, as a treatment for yeast infections, specifically mycoses, which are common fungal infections affecting the skin. Our study involved creating a special gel form of curcumin called a nanoemulsion, designed to enhance its delivery and effectiveness on the skin.
The formulation included an oil phase that worked to improve curcumin's stability and absorption through the skin. We evaluated various characteristics of the nanoemulsion, such as droplet size and stability, confirming that our gel formulation was effective in delivering curcumin.
In tests against Candida albicans, a common yeast responsible for infections, the curcumin nanoemulsion gel showed promising results, creating larger areas of inhibition compared to a commercially available treatment. This suggests that curcumin could be not only effective but also a better alternative for treating yeast infections.
Overall, the prepared nanoemulsion gel demonstrated improved skin penetration and bioavailability of curcumin, offering a beneficial approach for mycotic patients. The findings indicate potential advantages for curcumin in treating fungal infections, although its combination with other ingredients makes isolating its singular effects a bit tricky.
The formulation included an oil phase that worked to improve curcumin's stability and absorption through the skin. We evaluated various characteristics of the nanoemulsion, such as droplet size and stability, confirming that our gel formulation was effective in delivering curcumin.
In tests against Candida albicans, a common yeast responsible for infections, the curcumin nanoemulsion gel showed promising results, creating larger areas of inhibition compared to a commercially available treatment. This suggests that curcumin could be not only effective but also a better alternative for treating yeast infections.
Overall, the prepared nanoemulsion gel demonstrated improved skin penetration and bioavailability of curcumin, offering a beneficial approach for mycotic patients. The findings indicate potential advantages for curcumin in treating fungal infections, although its combination with other ingredients makes isolating its singular effects a bit tricky.
Read More
We examined the effects of turmeric, specifically its active compound curcumin, in treating yeast infections stemming from oral mucositis in patients undergoing chemotherapy and radiotherapy. The study was a randomized trial involving 30 participants, divided into three groups. One group received a standard antifungal treatment, while another group was treated with low-level laser therapy (photobiomodulation), and the last group was given a combination of a blue LED light and curcumin as a photosensitizer.
Our findings highlighted that both the low-level laser therapy and the curcumin therapy led to a reduction in the severity of oral mucositis and associated pain levels. Notably, the group receiving curcumin combined with blue LED treatment showed significant early improvement, especially in reducing yeast levels from the Candida species. This suggests that turmeric, when enhanced by light therapy, can be effective against oral yeast infections linked to mucositis.
While we also observed some benefits from conventional antifungal treatment, the results demonstrated that curcumin has a notable antimicrobial effect, particularly against yeast infections. However, it’s essential to recognize that the results stemmed from a combination therapy, making it challenging to pinpoint turmeric's effect independently.
Our findings highlighted that both the low-level laser therapy and the curcumin therapy led to a reduction in the severity of oral mucositis and associated pain levels. Notably, the group receiving curcumin combined with blue LED treatment showed significant early improvement, especially in reducing yeast levels from the Candida species. This suggests that turmeric, when enhanced by light therapy, can be effective against oral yeast infections linked to mucositis.
While we also observed some benefits from conventional antifungal treatment, the results demonstrated that curcumin has a notable antimicrobial effect, particularly against yeast infections. However, it’s essential to recognize that the results stemmed from a combination therapy, making it challenging to pinpoint turmeric's effect independently.
Read More
9
We examined how curcumin, a compound found in turmeric, influences yeast infections, particularly focusing on its interaction with dodecanol in the wild-type yeast, Saccharomyces cerevisiae.
The research showed that while dodecanol alone had a temporary antifungal effect, combining it with curcumin led to a significant increase in its efficacy, even preventing the yeast cells from recovering.
Additionally, we noticed that curcumin appeared to inhibit the yeast's ability to pump out drugs by reducing the expression of certain genes responsible for drug efflux. This means that curcumin helps retain the antifungal agent in the cells, making it more effective.
Overall, our findings suggest that curcumin plays a vital role in enhancing the antifungal action of certain treatments on yeast infections.
The research showed that while dodecanol alone had a temporary antifungal effect, combining it with curcumin led to a significant increase in its efficacy, even preventing the yeast cells from recovering.
Additionally, we noticed that curcumin appeared to inhibit the yeast's ability to pump out drugs by reducing the expression of certain genes responsible for drug efflux. This means that curcumin helps retain the antifungal agent in the cells, making it more effective.
Overall, our findings suggest that curcumin plays a vital role in enhancing the antifungal action of certain treatments on yeast infections.
Read More
8
Turmeric aids in yeast infection treatment
We conducted a study to examine how turmeric, specifically in the form of nano-curcumin, influences the growth of yeast infections caused by Candida albicans and Enterococcus faecalis. Our research utilized extracted single-canal maxillary anterior teeth, which were inoculated with the harmful microorganisms. We then applied various treatments, including nano-curcumin, ultrasound waves, and a standard antimicrobial solution—5.25% sodium hypochlorite—to compare their efficacy in reducing biofilm formation.
During our observations, we found that the SACT treatment combining nano-curcumin with ultrasound waves significantly reduced both the number of yeast colonies and the thickness of the biofilm compared to the control and ultrasound-only groups. While the results showed that nano-curcumin by itself had some effect, it was the combination with ultrasound that truly stood out. Our findings suggested that SACT might be nearly as effective as traditional treatments like sodium hypochlorite, providing an alternative approach for managing these stubborn infections.
Overall, it seems that turmeric, particularly when paired with ultrasound waves, has promising potential in the fight against yeast infections.
During our observations, we found that the SACT treatment combining nano-curcumin with ultrasound waves significantly reduced both the number of yeast colonies and the thickness of the biofilm compared to the control and ultrasound-only groups. While the results showed that nano-curcumin by itself had some effect, it was the combination with ultrasound that truly stood out. Our findings suggested that SACT might be nearly as effective as traditional treatments like sodium hypochlorite, providing an alternative approach for managing these stubborn infections.
Overall, it seems that turmeric, particularly when paired with ultrasound waves, has promising potential in the fight against yeast infections.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Amazing results
2 people found this helpful
I was struggling with yeast infections and warts, but now the results are astonishing. Thank you very much.
Read More
9
Highly recommended
1 people found this helpful
This is excellent for treating yeast infections. I highly recommend it!
Read More
7.5
Effective against infections
1 people found this helpful
I’ve used this product several times, and it effectively combats yeast infections, particularly in the urinary tract. It’s high quality, packed with antioxidants, and the inflammation decreases with use. The taste is also acceptable.
Read More
Frequently Asked Questions
9
Amazing results
2 people found this helpful
I was struggling with yeast infections and warts, but now the results are astonishing. Thank you very much.
7.5
Effective against infections
1 people found this helpful
I’ve used this product several times, and it effectively combats yeast infections, particularly in the urinary tract. It’s high quality, packed with antioxidants, and the inflammation decreases with use. The taste is also acceptable.
9
Highly recommended
1 people found this helpful
This is excellent for treating yeast infections. I highly recommend it!
9
We explored the effectiveness of curcumin, a compound in turmeric, as a treatment for yeast infections, specifically mycoses, which are common fungal infections affecting the skin. Our study involved creating a special gel form of curcumin called a nanoemulsion, designed to enhance its delivery and effectiveness on the skin.
The formulation included an oil phase that worked to improve curcumin's stability and absorption through the skin. We evaluated various characteristics of the nanoemulsion, such as droplet size and stability, confirming that our gel formulation was effective in delivering curcumin.
In tests against Candida albicans, a common yeast responsible for infections, the curcumin nanoemulsion gel showed promising results, creating larger areas of inhibition compared to a commercially available treatment. This suggests that curcumin could be not only effective but also a better alternative for treating yeast infections.
Overall, the prepared nanoemulsion gel demonstrated improved skin penetration and bioavailability of curcumin, offering a beneficial approach for mycotic patients. The findings indicate potential advantages for curcumin in treating fungal infections, although its combination with other ingredients makes isolating its singular effects a bit tricky.
The formulation included an oil phase that worked to improve curcumin's stability and absorption through the skin. We evaluated various characteristics of the nanoemulsion, such as droplet size and stability, confirming that our gel formulation was effective in delivering curcumin.
In tests against Candida albicans, a common yeast responsible for infections, the curcumin nanoemulsion gel showed promising results, creating larger areas of inhibition compared to a commercially available treatment. This suggests that curcumin could be not only effective but also a better alternative for treating yeast infections.
Overall, the prepared nanoemulsion gel demonstrated improved skin penetration and bioavailability of curcumin, offering a beneficial approach for mycotic patients. The findings indicate potential advantages for curcumin in treating fungal infections, although its combination with other ingredients makes isolating its singular effects a bit tricky.
8
Turmeric aids in yeast infection treatment
We conducted a study to examine how turmeric, specifically in the form of nano-curcumin, influences the growth of yeast infections caused by Candida albicans and Enterococcus faecalis. Our research utilized extracted single-canal maxillary anterior teeth, which were inoculated with the harmful microorganisms. We then applied various treatments, including nano-curcumin, ultrasound waves, and a standard antimicrobial solution—5.25% sodium hypochlorite—to compare their efficacy in reducing biofilm formation.
During our observations, we found that the SACT treatment combining nano-curcumin with ultrasound waves significantly reduced both the number of yeast colonies and the thickness of the biofilm compared to the control and ultrasound-only groups. While the results showed that nano-curcumin by itself had some effect, it was the combination with ultrasound that truly stood out. Our findings suggested that SACT might be nearly as effective as traditional treatments like sodium hypochlorite, providing an alternative approach for managing these stubborn infections.
Overall, it seems that turmeric, particularly when paired with ultrasound waves, has promising potential in the fight against yeast infections.
During our observations, we found that the SACT treatment combining nano-curcumin with ultrasound waves significantly reduced both the number of yeast colonies and the thickness of the biofilm compared to the control and ultrasound-only groups. While the results showed that nano-curcumin by itself had some effect, it was the combination with ultrasound that truly stood out. Our findings suggested that SACT might be nearly as effective as traditional treatments like sodium hypochlorite, providing an alternative approach for managing these stubborn infections.
Overall, it seems that turmeric, particularly when paired with ultrasound waves, has promising potential in the fight against yeast infections.
7
We conducted an in-depth review to understand whether curcumin, a natural compound found in turmeric, could serve as an effective alternative treatment for oral yeast infections, specifically oral candidiasis. Our research involved sifting through various studies that used a method called antimicrobial photodynamic therapy (aPDT) combined with curcumin to see its effects on Candida species, the fungi responsible for these infections.
From an initial pool of 757 studies, we focused on 26 that met our strict criteria, including laboratory studies and clinical trials. Our findings revealed that in several lab-based tests, curcumin-mediated aPDT completely eliminated yeast cells in some cases. However, for biofilms, which are clusters of yeast that can be more resistant to treatment, we only observed partial growth inhibition and reduction in biofilm mass.
When examining the effectiveness in live animal models, the results were encouraging, with notable antifungal activity observed. Yet, while the preclinical insights are promising, we found that the clinical implications still require further exploration through additional randomized control trials.
In summary, while curcumin shows potential in battling oral candidiasis, we are clear that more research is essential before it can be established as a standard treatment option.
From an initial pool of 757 studies, we focused on 26 that met our strict criteria, including laboratory studies and clinical trials. Our findings revealed that in several lab-based tests, curcumin-mediated aPDT completely eliminated yeast cells in some cases. However, for biofilms, which are clusters of yeast that can be more resistant to treatment, we only observed partial growth inhibition and reduction in biofilm mass.
When examining the effectiveness in live animal models, the results were encouraging, with notable antifungal activity observed. Yet, while the preclinical insights are promising, we found that the clinical implications still require further exploration through additional randomized control trials.
In summary, while curcumin shows potential in battling oral candidiasis, we are clear that more research is essential before it can be established as a standard treatment option.
7
We examined curcumin, a natural compound from turmeric, to assess its effects on yeast infections, particularly those caused by Candida. This compound is widely known for its various health benefits, including antioxidant and anti-inflammatory properties. Our focus was on its antifungal capabilities, given its potential to combat candidiasis.
We utilized a systematic review approach, sourcing data from reputable databases like PubMed and Google Scholar. Our analysis revealed that while curcumin shows promising antifungal activity, its effectiveness can be notably enhanced when combined with other drug formulations, especially those using nanoparticles. This targeted approach increases absorption and ensures a more controlled release, making it a compelling strategy for treating fungal infections.
However, it is important to recognize that simply using curcumin alone may not have as significant an effect when dealing with resistant strains of yeast. Nonetheless, incorporating curcumin into innovative treatment plans offers a potential pathway to improve outcomes in managing Candida infections.
We utilized a systematic review approach, sourcing data from reputable databases like PubMed and Google Scholar. Our analysis revealed that while curcumin shows promising antifungal activity, its effectiveness can be notably enhanced when combined with other drug formulations, especially those using nanoparticles. This targeted approach increases absorption and ensures a more controlled release, making it a compelling strategy for treating fungal infections.
However, it is important to recognize that simply using curcumin alone may not have as significant an effect when dealing with resistant strains of yeast. Nonetheless, incorporating curcumin into innovative treatment plans offers a potential pathway to improve outcomes in managing Candida infections.
References
- Kubizna M, Dawiec G, Wiench R. Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy on spp.-A Systematic Review. Int J Mol Sci. 2024;25. doi:10.3390/ijms25158136
- Al Fatease A, Alqahtani A, Khan BA, Mohamed JMM, Farhana SA. Preparation and characterization of a curcumin nanoemulsion gel for the effective treatment of mycoses. Sci Rep. 2023;13:22730. doi:10.1038/s41598-023-49328-2
- Yasini Z, Roghanizad N, Fazlyab M, Pourhajibagher M. Ex vivo efficacy of sonodynamic antimicrobial chemotherapy for inhibition of Enterococcus faecalis and Candida albicans biofilm. Photodiagnosis Photodyn Ther. 2022;40:103113. doi:10.1016/j.pdpdt.2022.103113
- de Cássia Dias Viana Andrade R, Azevedo Reis T, Rosa LP, de Oliveira Santos GP, da CristinaSilva F. Comparative randomized trial study about the efficacy of photobiomodulation and curcumin antimicrobial photodynamic therapy as a coadjuvant treatment of oral mucositis in oncologic patients: antimicrobial, analgesic, and degree alteration effect. Support Care Cancer. 2022;30:7365. doi:10.1007/s00520-022-07127-x
- W Figueira L, de Oliveira JR, Netto AA, S Zamarioli LD, Marcucci MC, et al. L. helps macrophages to control opportunistic micro-organisms during host-microbe interactions. Future Microbiol. 2020;15:1237. doi:10.2217/fmb-2019-0297
- Jordão CC, Viana de Sousa T, Inêz Klein M, Mendonça Dias L, Pavarina AC, et al. Antimicrobial photodynamic therapy reduces gene expression of Candida albicans in biofilms. Photodiagnosis Photodyn Ther. 2020;31:101825. doi:10.1016/j.pdpdt.2020.101825
- Cheraghipour K, Ezatpour B, Masoori L, Marzban A, Sepahvand A, et al. Anti-Candida Activity of Curcumin: A Systematic Review. Curr Drug Discov Technol. 2021;18:379. doi:10.2174/1570163817666200518074629
- Andrade JT, Fantini de Figueiredo G, Cruz LF, Eliza de Morais S, Souza CDF, et al. Efficacy of curcumin in the treatment of experimental vulvovaginal candidiasis. Rev Iberoam Micol. 2019;36:192. doi:10.1016/j.riam.2019.01.003
- Daliri F, Azizi A, Goudarzi M, Lawaf S, Rahimi A. In vitro comparison of the effect of photodynamic therapy with curcumin and methylene blue on Candida albicans colonies. Photodiagnosis Photodyn Ther. 2019;26:193. doi:10.1016/j.pdpdt.2019.03.017
- Yamawaki C, Oyama M, Yamaguchi Y, Ogita A, Tanaka T, et al. Curcumin potentiates the fungicidal effect of dodecanol by inhibiting drug efflux in wild-type budding yeast. Lett Appl Microbiol. 2019;68:17. doi:10.1111/lam.13083
